International Review of Ophthalmology

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The role of cytokines in complicated cataract caused by uveitis

ZHANG Ying-lei, ZHU Xiang-jia, LU Yi.   

  1. Department of Ophthalmology, Fudan University, Eye, Ear, Nose and Throat Hospital, Shanghai 200031,China
  • Received:2015-12-19 Online:2016-06-25 Published:2016-06-26
  • Contact: LU Yi, Email: luyieent@126.com

Abstract:

The role of cytokines (CD4+T-associated cytokines, VEGF, pro-inflammatory cytokine, etc) in inflammation has been demonstrated, and a high-level expression has been showed in active period. Postoperative complications of complicated cataract in patients with non-infectious uveitis are frequent and severe because of the recurrent inflammation. Multiple cytokines are involved in the pathogenesis of complications, but the specific mechanism is still unclear. In recent years, more studies about cytokines expression and its function have been performed. In addition, the efficacy of the treatments specific to cytokines have been published and satisfactory outcomes have been achieved.